Neoadjuvant chemotherapy and cytoreductive surgery in epithelial ovarian cancer
نویسندگان
چکیده
منابع مشابه
Neoadjuvant chemotherapy for advanced epithelial ovarian cancer.
The historical standard treatment paradigm for advanced epithelial ovarian cancer is surgical staging followed by adjuvant platinum- and taxane-based chemotherapy. It is well established that patients gain a survival advantage when optimal surgical debulking is achieved; surgical intervention that leaves bulky disease does not confer the same advantage. Thus, when optimal cytoreductive surgery ...
متن کاملCytoreductive surgery and perioperative intraperitoneal chemotherapy in recurrent ovarian cancer.
BACKGROUND AND AIMS Cytoreductive surgery with perioperative intraperitoneal chemotherapy is another approach for recurrent ovarian cancer. The purpose of the study was to assess the feasibility and the effect of cytoreduction and perioperative intraperitoneal chemotherapy in recurrent ovarian cancer. PATIENTS AND METHODS Twenty-nine women with recurrent ovarian cancer underwent cytoreductive...
متن کاملDoes neoadjuvant chemotherapy plus cytoreductive surgery improve survival rates in patients with advanced epithelial ovarian cancer compared with cytoreductive surgery alone?
PURPOSE The purpose of this study was to compare the outcomes of interval debulking surgery after neoadjuvant chemotherapy (NAC/IDS) with primary debulking surgery (PDS) in patients diagnosed with advanced epithelial ovarian cancer (EOC). METHODS A total of 292 patients with IIIC and IV disease stages, who were treated with either NAC/IDS or PDS between 1995 and 2012 were retrospectively revi...
متن کاملMaximal cytoreductive effort in epithelial ovarian cancer surgery.
The surgical management of advanced epithelial ovarian cancer involves cytoreduction, or removal of grossly-evident tumor. Residual disease after surgical cytoreduction of ovarian cancer has been shown to be strongly associated with survival. The goal of surgery is "optimal" surgical cytoreduction, which is generally defined as residual disease of 1 cm or less. However, the designation of "opti...
متن کاملCytoreductive surgery in ovarian cancer
As the overall prognosis for patients with ovarian cancer is poor, the management of this condition should be restricted to expert multi-disciplinary teams in gynaecological oncology. Apparent early stage ovarian cancer requires accurate and complete staging so that potential sites for metastases are not missed. Omitting adequate staging may have significant consequences including a negative im...
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ژورنال
عنوان ژورنال: World Journal of Obstetrics and Gynecology
سال: 2013
ISSN: 2218-6220
DOI: 10.5317/wjog.v2.i4.153